If so, you can try troubleshooting it with the following suggestions: If you are unsure whether or not you have the Adobe plug-in installed, go to the 'Help' menu in Safari and choose 'Installed Plugins' to see if it is available in the list. It is required to view PDFs in some other browsers besides Safari, which makes it a required installation for some people.
Adobe has had its 'Adobe Reader' (Acrobat Reader) plug-in available for the Mac long before Safari and OS X were available, and has maintained development of it. This problem can happen for a variety of reasons, the most prominent of which are issues with Adobe's 'Reader' plug-in. Despite this, a number of people are having problems viewing PDFs in Safari, in which the browser will show a blank white or black screen instead of the selected PDF file. Safari is one of these applications, and when you click on a PDF link you should be able to view PDFs without having to load any plug-ins or other software. Apple's built-in support for the PDF format has allowed for a number of programs to easily implement its use.